Education
February 2014 - Dr. rer. nat. (Ph.D.) in Nutritional Sciences, University of Hohenheim, Stuttgart, Germany
Thesis: Investigations on the biological availability and activity of curcumin in vivo
2009 - Master of Science in Nutrition and Home Economics, Christian-Albrechts-University Kiel, Kiel, Germany
Professional experience
2014 - present: Postdoctoral fellow, Division Biofunctionality and Safety of Food, Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
2009 - 2014: Doctoral student, Division Biofunctionality and Safety of Food, Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
Awards and affiliations
2010 - Recipient of the Helmut Erbersdobler-Award for the best M.Sc. thesis in Food Sciences at Christian-Albrechts-University Kiel, Kiel, Germany
Member of the Society of Nutrition and Food Science
Publications
Original articles
Dützmann, S., Schiborr, C., Kocher, A., Pilatus, U., Hattingen, E., Weissenberger, J., Gessler, F., Quick-Weller, J., Franz, K., Seifert, V., Frank, J. & Senft, C. (2016) Intratumoral concentrations and effects of orally administered micellar curcuminoids in glioblastoma patients. Nutrition and Cancer (published online ahead of print), IF 2.322.
Kocher, A., Bohnert, L., Schiborr, C. & Frank, J. (2016) Highly bioavailable micellar curcuminoids accumulate in blood, are safe and do not reduce blood lipids and inflammation markers in moderately hyperlipidaemic individuals. Mol Nutr Food Res (published online ahead of print), IF 4.603.
Bortel, N., Armeanu-Ebinger, S., Schmid, E., Kirchner, B., Frank, J., Kocher, A., Schiborr, C., Warmann, S.W., Fuchs, J. & Ellerkamp, V. (2015). Effects of curcumin in pediatric epithelial liver tumors: inhibition of tumor growth and alpha-fetoprotein in vitro and in vivo involving the NFkappaB and the beta-catenin pathways. Oncotarget (accepted for publication), IF 6.359.
Hagl, S., Kocher, A., Schiborr, C., Kolesova, N., Frank, J., & Eckert, G. P. (2015) Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice - Impact on bioavailability. Neurochemistry International, (published online), IF 3.092.
Kocher, A., Hagl, S., Schiborr, C., Eckert, G. P., & Frank, J. (2015) Concentrations of total curcuminoids in plasma, but not liver and kidney, are higher in 18- than in 3-months old mice. NFS Journal 1: 3-8.
Kocher, A., Schiborr, C., Behnam, D., & Frank, J. (2015). The oral bioavailability of curcuminoids in healthy humans is markedly enhanced by micellar solubilisation but not further improved by simultaneous ingestion of sesamin, ferulic acid, naringenin and xanthohumol. J Funct Foods 14: 183-191, IF 4.480.
Hagl, S., Heinrich, M., Kocher, A., Schiborr, C., Frank, J., & Eckert, G. P. (2014). Curcumin micelles improve mitochondrial function in a mouse model of Alzheimer's disease. The Journal of Prevention of Alzheimer’s Disease 1: 80-83.
Schiborr, C., Kocher, A., Behnam, D., Jandasek, J., Toelstede, S., & Frank, J. (2014). The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes. Mol Nutr Food Res 58: 516-527, IF 4.909.
Hagl, S., Kocher, A., Schiborr, C., Eckert, S., Ciobanu, I., Birringer, M., El-Askary, H., Helal, A., Khayyal, M. T., Frank, J., Müller, W. E., & Eckert, G. P. (2013) Rice bran extract protects from mitochondrial dysfunction in guinea pig brains. Pharmacol Res 76: 17-27, IF 4.436
Schiborr, C., Schwamm, D., Kocher, A., Rimbach, G., Eckert, G. P., & Frank J. (2013) The senescence-accelerated mouse - prone 8 is not a suitable model for the investigation of cardiac inflammation and oxidative stress and their modulation by dietary phytochemicals. Pharmacol Res 74: 113-120, IF 4.436
Eckert, G. P., Schiborr, C., Hagl, S., Abdel-Kader, R., Müller, W. E., Rimbach, G., & Frank, J. (2013). Curcumin prevents mitochondrial dysfunction in the brain of the senescence-accelerated mouse - prone 8. Neurochemistry International 65: 595-602, IF 2.857.
Schiborr, C., Eckert, G. P., Weissenberger, J., Müller, W. E., Schwamm, D., Grune, T., Rimbach, G. & Frank, J. (2010) Cardiac oxidative stress and inflammation are similar in SAMP8 and SAMR1 mice and unaltered by curcumin and Ginkgo biloba extract intake. Curr Pharmaceut Biotechnol 11: 861-867, IF 3.455.
Schiborr, C., Eckert, G. P., Rimbach, G. & Frank, J. (2010) A validated method for the quantification of curcumin in plasma and brain tissue by fast narrow-bore high-performance liquid chromatography with fluorescence detection. Anal Bioanal Chem 397: 1917-25, IF 3.841.
Book chapters
Kocher, A., Schiborr, C., Weber, D., Grune, T. & Frank, J. (2013) The bioavailability and antioxidant activity of curcuminoids and carotenoids in humans. In: "Food Oxidants and Antioxidants: Chemical, Biological, and Functional Properties", Bartosz, G., ed., CRC Press (ISBN 978-1-439-88241-2).